The character was written out of Family Guy largely at the behest of Alex Borstein, who complained the deep gravelly female voice of Loretta was too demanding of her voice.
The Cleveland Show and Death
Despite the amicable parting on Family Guy, The "Pilot" of The Cleveland Show showed Loretta as being spiteful towards Cleveland during their divorce, taking possession of their old house while leaving Jr. with him. Following her death, she leaves her estate to Jr. in "You're the Best Man, Cleveland Brown" under the stipulation that none of it is used for her ex-husband.
Loretta's death occurred in "Gone With the Wind" when she was killed when Peter accidentally dropped a brontosaurus skeleton onto her house in a parody of the running gag where Peter causes Cleveland's house to be destroyed and him falling onto the lawn in the bath tub, but this time, she fell out of the tub and broke her neck. Cleveland's new wife Donna, claims that Peter told her that Loretta had also slept with Mayor Adam West, Ollie Williams, Frank Sinatra Jr., and the Greased-up Deaf Guy.
Post-Death Family Guy Mentions
Peter crank-calls Cleveland in "Baby Got Black" and pretends to be Loretta, having faked her own death to trick the IRS.
- In Mind over Murder This marks the debut of Cleveland Brown's first wife, Loretta Brown.
- FG104 "Mind Over Murder"
- FG203 "Da Boom"
- FG205 "Love Thy Trophy"
- FG207 "The King Is Dead"
- FG208 "I Am Peter, Hear Me Roar"
- FG211 "A Picture's Worth a Thousand Bucks"
- FG212 "Fifteen Minutes of Shame"
- FG301 "The Thin White Line"
- FG304 "One if by Clam, Two if by Sea"
- FG306 "Death Lives"
- FG308 "The Kiss Seen Around the World"
- FG315 "Ready, Willing, and Disabled"
- FG319 "Stuck Together, Torn Apart"
- FG403 "Blind Ambition"
- FG405 "The Cleveland-Loretta Quagmire"
- FG425 "You May Now Kiss the...Uh...Guy Who Receives" (cameo at the wedding)
- FG701 "Love, Blactually"
- FG1218 "Baby Got Black" (mentioned)
- FG1317 "Fighting Irish (mentioned)